Relation Results

Summary

Name DST
Full Name Dystonin
Synonyms 230 kDa bullous pemphigoid antigen, 230/240 kDa bullous pemphigoid antigen, Bullous pemphigoid antigen 1, BPA, Bullous pemphigoid antigen, Dystonia musculorum protein, Hemidesmosomal plaque protein | BP230, BP240, BPAG1, DMH, DT, KIAA0728
Primary ID Q03001
Links - -
Type protein
Relations 2
Function Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring eith ...
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Type: Score: Layout: SPV 
0.20.2IRF1DSTIRF2

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Relations
Regulator
Mechanism
target
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+ IRF1down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation DST 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-254492 Homo sapiens
pmid sentence
Transient transfection studies with BPAG1 promoter-luciferase reporter gene plasmids and IRF1 and IRF2 expression plasmids revealed that IRF1 and IRF2 directly down-regulated BPAG1 gene transcription in cultured normal human epidermal keratinocytes.
Publications: 1 Organism: Homo Sapiens
+ IRF2down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation DST 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-254493 Homo sapiens
pmid sentence
Transient transfection studies with BPAG1 promoter-luciferase reporter gene plasmids and IRF1 and IRF2 expression plasmids revealed that IRF1 and IRF2 directly down-regulated BPAG1 gene transcription in cultured normal human epidermal keratinocytes.
Publications: 1 Organism: Homo Sapiens
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