| Name
|
 HHEX
|
| Full Name |
Hematopoietically-expressed homeobox protein HHEX |
| Synonyms |
Homeobox protein HEX, Homeobox protein PRH | HEX, PRH, PRHX |
| Primary ID |
Q03014 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
2 |
| Pathways |
Acute Myeloid Leukemia, FLT3 in AML |
| Function |
Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). May play a role in hematopoietic differentiation (PubMed:8096636). |
4.0
transcriptional regulation