Acute Myeloid Leukemia

Pathway ID: SIGNOR-AMLView in NDEx

Curated by: Livia Perfetto

148 Seed Entities

Organism:
Name Primary ID
all-trans-retinoic acid CHEBI:15367
KDM5A P29375
PARP1 P09874
PTEN P60484
NCOR2 Q9Y618
DNMT3A Q9Y6K1
NUP98 Fusion SIGNOR-FP16
BCL2 P10415
MEK1/2 SIGNOR-PF25
JUN P05412
KITLG P21583
BAD Q92934
PTPRJ Q12913
miR-155 URS000062749E_9606
RUNX1 Q01196
PTPRC P08575
CDKN2A Q8N726
INPP5D Q92835
MTOR P42345
FBXW7 Q969H0
NPM1 P06748
FLT3LG P49771
MLL-ENL SIGNOR-FP7
MECOM Q03112
PIM1 P11309
GRB2 P62993
NCOA1 Q15788
NOTCH SIGNOR-PF30
KLF2 Q9Y5W3
BCL2L1 Q07817
MDM2 Q00987
RELA Q04206
SIRT1 Q96EB6
STAT5A P42229
MYC P01106
AML1-ETO SIGNOR-FP1
STAT3 P40763
NOTCH1 P46531
EZH2 Q15910
PI3K SIGNOR-C156
SP1 P08047
MLL Fusion SIGNOR-FP14
PDPK1 O15530
CDKN1B P46527
miR-199a URS0000759977_9606
HOXA9 P31269
SH2B3 Q9UQQ2
TWIST1 Q15672
CDK6 Q00534
IGF1 P05019
SRSF2 Q01130
AMPK SIGNOR-C15
FZD4 Q9ULV1
DNA_repair SIGNOR-PH57
ZBTB16 Q05516
GRB10 Q13322
CDKN2A P42771
Differentiation SIGNOR-PH37
PML-RARalpha SIGNOR-FP2
CBFbeta-MYH11 SIGNOR-FP3
USP22 Q9UPT9
EP300 Q09472
FOXO SIGNOR-PF27
NFY SIGNOR-C1
CUX1 P39880
MLL-AF9 SIGNOR-FP5
BAX Q07812
ASXL1 Q8IXJ9
PTPN11 Q06124
PAX7 P23759
TET2 Q6N021
CBLB Q13191
RAD21 O60216
PHF6 Q8IWS0
NRAS P01111
JAK2 O60674
KIT P10721
BRAF P15056
DVL1 O14640
miR-132 URS00001F4E81_9606
CSF2RA/CSF2RB SIGNOR-C212
PIP3 CHEBI:16618
PIK3IP1 Q96FE7
RXRA P19793
PTPN6 P29350
SHC1 P29353
mir-143 URS0000008A99_9606
AEP complex SIGNOR-C117
NfKb-p65/p50 SIGNOR-C13
diarsenic trioxide CHEBI:30621
RARA P10276
MIR1-1 URS000075CF56_9606
FLT3 P36888
RAC1 P63000
Apoptosis SIGNOR-PH2
prostaglandin E2(1-) CHEBI:606564
ETV6 P41212
ID1 P41134
FOS P01100
Proliferation SIGNOR-PH4
BCORL1 Q5H9F3
HHEX Q03014
UBTF P17480
IDH2 P48735
PTGS2 P35354
SOX4 Q06945
CDKN1A P38936
CDK1 P06493
CTNNB1 P35222
HES1 Q14469
CCND1 P24385
miR-338 URS000075E706_9606
MEN1 O00255
ERK1/2 SIGNOR-PF1
2-oxoglutarate(2-) CHEBI:16810
AP1 SIGNOR-C154
KAT5 Q92993
DOT1L Q8TEK3
MAPK8 P45983
MCL1 Q07820
KRAS P01116
glucose CHEBI:17234
BCR-ABL SIGNOR-FP6
PIM SIGNOR-PF34
CBL P22681
WT1 P19544
MEIS1 O00470
CCNA1 P78396
SNW1 Q13573
GSK3B P49841
SPI1 P17947
CTBP1 Q13363
RAD51 Q06609
TP53 P04637
SOS1 Q07889
hsa-mir-223 URS000037EC34_9606
EGFR P00533
AKT SIGNOR-PF24
CEBPB P17676
BCOR Q6W2J9
IDH1 O75874
CEBPA P49715
MLL-AF4 SIGNOR-FP4
mir-10b URS00004CAC40_9606
midostaurin CHEBI:63452
MECP2 P51608
ASXL2 Q76L83
BAK1 Q16611