+ |
EGR1 | up-regulates quantity by expression
transcriptional regulation
|
COL10A1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251921 |
|
|
Homo sapiens |
|
pmid |
sentence |
21931594 |
Egr-1 induced a time-dependent ECM gene expression program, with the number of ECM genes increasing >2.5-fold (from 16 to 41) between 24 and 48 h. Genes in this group include those coding for multiple collagens (COL4A1, COL4A2, COL11A1, COL7A1, COL10A1) |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SIRT1 | down-regulates quantity by repression
transcriptional regulation
|
COL10A1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255141 |
|
|
Homo sapiens |
|
pmid |
sentence |
21337390 |
The inhibition of SIRT1 by siRNA induced OA-like gene expression changes, namely the significant down-regulation of aggrecan and up-regulation of COL10A1 and ADAMTS-5. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |