Summary

Name LIPE
Full Name Hormone-sensitive lipase
Synonyms HSL
Primary ID Q05469
Links - -
Type protein
Relations 9
Function In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation LIPE 0.22
Publications: 3 Organism: Mus Musculus
+ down-regulates img/direct_inhibition.png phosphorylation LIPE 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation LIPE 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation LIPE 0.28
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation LIPE 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation LIPE 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png phosphorylation LIPE 0.14
Publications: 1 Organism: Mus Musculus