Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-267454 |
|
|
Homo sapiens |
|
pmid |
sentence |
27692180 |
HIF-1 promotes glycolysis by transcriptionally upregulating GLUT1, GLUT3, HK1, and HK2. HIF-1 also suppresses oxidative phosphorylation by the upregulation of gene expression of BNIP3, BNIP3L, LDHA, and PDK1. In addition, HIF-1 can inhibit apoptosis by suppressing the expression of BID. |
|