| + |
NCOA4 | up-regulates 
binding
|
PPARG |
0.461 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-67687 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10347167 |
Identification of ara70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma. / ppargamma and ara70 interact in the absence of the ppargamma ligand 15-deoxy-delta12,14-prostaglandin j2, although the addition of exogenous ligand enhances this interaction. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NCOA4 | up-regulates
binding
|
AR |
0.854 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-67684 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10347167 |
We demonstrated that ara70 and ar physically interact and that ara70 can function as an androgen-dependent coactivator for ar. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KLK2 | up-regulates 
|
NCOA4 |
0.312 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-202885 |
|
|
Homo sapiens |
Prostate Gland Cancer Cell |
| pmid |
sentence |
| 24122203 |
Klk2may cooperate with the ar coregulator, ara70, to enhance ar transactivation |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NCOA4 | up-regulates quantity by expression
transcriptional regulation
|
KLK3 |
0.334 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253659 |
|
|
Homo sapiens |
PC-J Cell |
| pmid |
sentence |
| 18649734 |
The PSA promoter activity was detected by transient expression assay in the PC-J and LNCaP cells but not in androgen insensitive PC-3 cells. When the PC-J cells were cotransfected with androgen receptor, androgen receptor coactivators and PSA reporter vector cells, the reporter assays indicated that nuclear receptor coactivator 4 (NCOA4) but not androgen receptor activator 24 (ARA24) increased the sensitivity and maximum stimulation of dihydrotestosterone (DHT)-inducing PSA promoter activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
NCOA4
- 
- 