4.0
Summary
| Name |  GAMT
|
| Full Name | Guanidinoacetate N-methyltransferase |
| Synonyms | GAMT_HUMAN | |
| Primary ID | Q14353 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Pathways | Rett syndrome |
| Function | Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor (PubMed:26003046, PubMed:24415674, PubMed:26319512). Important in nervous system development (PubMed:24415674). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | GAMT | up-regulates 
|
Neurite_outgrowth | 0.7 |
| Publications: | 1 | Organism: | In Vitro | |
| Pathways: | Rett syndrome | |||
| + | GAMT | up-regulates
|
Neuron_maturation | 0.7 |
| Publications: | 1 | Organism: | In Vitro | |
| Pathways: | Rett syndrome | |||
| + | MECP2 | up-regulates quantity by expression 
post transcriptional regulation
|
GAMT | 0.28 |
| Publications: | 1 | Organism: | Mus Musculus | |
| Pathways: | Rett syndrome | |||