Summary

Name MXD4
Full Name Max dimerization protein 4
Synonyms Max dimerizer 4, Class C basic helix-loop-helix protein 12, bHLHc12, Max-associated protein 4, Max-interacting transcriptional repressor MAD4 | BHLHC12, MAD4
Primary ID Q14582
Links - -
Type protein
Relations 2
Function Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding MXD4 0.496
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding MXD4 0.3
Publications: 1 Organism: Chlorocebus Aethiops