3.0
Summary
| Name |  PTPN14View Modifications |
| Full Name | Tyrosine-protein phosphatase non-receptor type 14 |
| Synonyms | Protein-tyrosine phosphatase pez | PEZ, PTPD2 |
| Primary ID | Q15678 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PTPN14 | down-regulates 
dephosphorylation
|
BCAR1 | 0.404 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPN14 | down-regulates activity
dephosphorylation
|
CAV1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPN14 | down-regulates activity
dephosphorylation
|
STAT3 | 0.275 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |