Relation Results

Summary

Name IMMT
Full Name MICOS complex subunit MIC60
Synonyms Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89 | HMP, MIC60, MINOS2
Primary ID Q16891
Links - -
Type protein
Relations 2
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junc ...
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Type: Score: Layout: SPV 
0.20.402PRKACAIMMTPINK1

Modifications Tables

Relations

Regulator
Mechanism
target
score
+ down-regulates activity img/direct_inhibition.png phosphorylation IMMT 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-266302 Ser528 ELQFRRLsQEQVDNF in vitro
pmid sentence
PKA directly phosphorylated the Ser528 residue of MIC60. Phosphorylation of MIC60 Interrupts Parkin Recruitment and Formation of the MICOS Complex
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png binding PINK1 0.402
Identifier Residue Sequence Organism Cell Line
SIGNOR-266301 in vitro
pmid sentence
MIC60 Is Crucial for Parkin Recruitment and Transiently Interacts with PINK1
Publications: 1 Organism: In Vitro
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