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Summary
Name
AKAP4
View Modifications
Full Name
A-kinase anchor protein 4
Synonyms
AKAP-4, A-kinase anchor protein 82 kDa, AKAP 82, hAKAP82, Major sperm fibrous sheath protein, HI, Protein kinase A-anchoring protein 4, PRKA4 | AKAP82
Primary ID
Q5JQC9
Links
-
-
Type
protein
Relations
2
Function
Major structural component of sperm fibrous sheath. Plays a role in sperm motility. {ECO:0000269|PubMed:9822690}.
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Refine search:
by mechanism
none
phosphorylation
by effect
none
unknown
up-regulates quantity by stabilization
by organism:
none
Homo sapiens
in vitro
by tissue:
none
by cell-line
none
spermatozoon
▶
Modifications Tables
AKAP4 as Target
Residue
Sequence
Modifier
Effect
Modification
Thr265
KERISPRtPASKIAS
MAPK1
unknown
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
MAPK1
phosphorylation
AKAP4
0.264
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-271861
Thr265
KERISPRtPASKIAS
Homo sapiens
Spermatozoon
pmid
sentence
27901058
Here we demonstrate that ERK1/2 phosphorylates proAKAP4 on Thr265 in human spermatozoa in vitro and in vivo
Publications:
1
Organism:
Homo Sapiens
+
STK33
up-regulates quantity by stabilization
phosphorylation
AKAP4
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-272956
in vitro
pmid
sentence
37146716
Differential phosphoproteomic analysis and in vitro kinase assay identified novel phosphorylation substrates of STK33, fibrous sheath components AKAP3 and AKAP4, whose expression levels decreased in testis after deletion of Stk33.
Publications:
1
Organism:
In Vitro