Relation Results

Summary

Name HABP4
Full Name Intracellular hyaluronan-binding protein 4
Synonyms IHABP-4, IHABP4, Ki-1/57 intracellular antigen
Primary ID Q5JVS0
Links - -
Type protein
Relations 13
Function RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, Pu ...
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Type: Score: Layout: SPV 
0.2940.3080.2960.2940.2970.2940.344PRKCBHABP4PRKCQPRKCZPRKCAPRKCGPRKCDMEF2C

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▶Modifications Tables

Relations
Regulator
Mechanism
target
score ℹ
+ PRKCBdown-regulates activity img/direct_inhibition.png phosphorylation HABP4 0.294
Identifier Residue Sequence Organism Cell Line
SIGNOR-249247 Thr354 RKPANDItSQLEINF Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Identifier Residue Sequence Organism Cell Line
SIGNOR-249253 Thr375 GRGARGGtRGGRGRI Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Publications: 2 Organism: Homo Sapiens
+ PRKCQdown-regulates activity img/direct_inhibition.png phosphorylation HABP4 0.308
Identifier Residue Sequence Organism Cell Line
SIGNOR-249250 Thr354 RKPANDItSQLEINF Homo sapiens
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Identifier Residue Sequence Organism Cell Line
SIGNOR-249256 Thr375 GRGARGGtRGGRGRI Homo sapiens
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Publications: 2 Organism: Homo Sapiens
+ PRKCZdown-regulates activity img/direct_inhibition.png phosphorylation HABP4 0.296
Identifier Residue Sequence Organism Cell Line
SIGNOR-249251 Thr354 RKPANDItSQLEINF Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Identifier Residue Sequence Organism Cell Line
SIGNOR-249257 Thr375 GRGARGGtRGGRGRI Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Publications: 2 Organism: Homo Sapiens
+ PRKCAdown-regulates activity img/direct_inhibition.png phosphorylation HABP4 0.294
Identifier Residue Sequence Organism Cell Line
SIGNOR-249246 Thr354 RKPANDItSQLEINF Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Identifier Residue Sequence Organism Cell Line
SIGNOR-249252 Thr375 GRGARGGtRGGRGRI Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Publications: 2 Organism: Homo Sapiens
+ PRKCGdown-regulates activity img/direct_inhibition.png phosphorylation HABP4 0.297
Identifier Residue Sequence Organism Cell Line
SIGNOR-249249 Thr354 RKPANDItSQLEINF Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Identifier Residue Sequence Organism Cell Line
SIGNOR-249255 Thr375 GRGARGGtRGGRGRI Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Publications: 2 Organism: Homo Sapiens
+ PRKCDdown-regulates activity img/direct_inhibition.png phosphorylation HABP4 0.294
Identifier Residue Sequence Organism Cell Line
SIGNOR-249248 Thr354 RKPANDItSQLEINF Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Identifier Residue Sequence Organism Cell Line
SIGNOR-249254 Thr375 GRGARGGtRGGRGRI Homo sapiens Hodgkin Lymphoma Cell
pmid sentence
We found a strong phosphorylation of Ki-1/57 by PKCalphabeta, PKCdelta, PKClambda/zeta, and especially by PKCsigma, however not by PKCmi. These data show that Ki-1/57 can serve in principal as a substrate for a wide variety of different PKC isoforms but also that its phosphorylation is strongest with PKCsigma. | This suggests that the two threonine residues present in this fragment (Thr354 and Thr375) might be the main target residues for phosphorylation by PKC in vitro. | Ki-1/57 Exits the Nucleus upon PMA Activation
Publications: 2 Organism: Homo Sapiens
+ HABP4down-regulates activity img/direct_inhibition.png binding MEF2C 0.344
Identifier Residue Sequence Organism Cell Line
SIGNOR-238283 Rattus norvegicus
pmid sentence
MEF2C DNA-binding activity is inhibited through its interaction with the regulatory protein Ki-1/57.
Publications: 1 Organism: Rattus Norvegicus
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