Summary

Name IL23R
Full Name Interleukin-23 receptor
Synonyms IL-23 receptor, IL-23R
Primary ID Q5VWK5
Links - -
Type protein
Relations 4
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

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Relations

Regulator Mechanism target score ℹ
+ IL23Rup-regulates img/indirect-activation.png STAT4 0.575
Publications: 1 Organism: Homo Sapiens
+ IL23Aup-regulates img/direct-activation.png binding IL23R 0.856
Publications: 1 Organism: Homo Sapiens
+ IL23Rup-regulates img/direct-activation.png binding JAK2 0.689
Publications: 1 Organism: Homo Sapiens
+ IL23Rup-regulates img/direct-activation.png binding TYK2 0.566
Publications: 1 Organism: Homo Sapiens