Relation Results

Summary

Name IL23R
Full Name Interleukin-23 receptor
Synonyms IL-23 receptor, IL-23R
Primary ID Q5VWK5
Links - -
Type protein
Relations 4
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells s ...
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Type: Score: Layout: SPV 
0.5890.5810.8610.7IL23RSTAT4TYK2IL23AJAK2

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Relations
Regulator
Mechanism
target
score ℹ
+ IL23Rup-regulates img/indirect-activation.png STAT4 0.589
Identifier Residue Sequence Organism Cell Line
SIGNOR-87838 Homo sapiens T-lymphocyte
pmid sentence
Il-23 activates the same jak-stat signaling molecules as il-12: jak2, tyk2, and stat1, -3, -4, and -5, but stat4 activation is substantially weaker and different dna-binding stat complexes form in response to il-23 compared with il-12.
Publications: 1 Organism: Homo Sapiens
+ IL23Rup-regulates img/direct-activation.png binding TYK2 0.581
Identifier Residue Sequence Organism Cell Line
SIGNOR-87841 Homo sapiens T-lymphocyte
pmid sentence
Il-23 activates the same jak-stat signaling molecules as il-12: jak2, tyk2, and stat1, -3, -4, and -5, but stat4 activation is substantially weaker and different dna-binding stat complexes form in response to il-23 compared with il-12.
Publications: 1 Organism: Homo Sapiens
+ IL23Aup-regulates img/direct-activation.png binding IL23R 0.861
Identifier Residue Sequence Organism Cell Line
SIGNOR-87805 Homo sapiens T-lymphocyte
pmid sentence
We identify a novel member of the hemopoietin receptor family as a subunit of the receptor for il-23, il-23r.
Publications: 1 Organism: Homo Sapiens
+ IL23Rup-regulates img/direct-activation.png binding JAK2 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-87808 Homo sapiens T-lymphocyte
pmid sentence
Il-23 activates the same jak-stat signaling molecules as il-12: jak2, tyk2, and stat1, -3, -4, and -5, but stat4 activation is substantially weaker and different dna-binding stat complexes form in response to il-23 compared with il-12.
Publications: 1 Organism: Homo Sapiens
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