Name	IL23A
Full Name	Interleukin-23 subunit alpha
Synonyms	IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19 \| SGRF
Primary ID	Q9NPF7
Links	- -
Type	protein
Relations	5
Function	Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.