Summary

Name CCDC102B
Full Name Coiled-coil domain-containing protein 102B
Synonyms | C18orf14
Primary ID Q68D86
Links - -
Type protein
Relations 4
Function During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion (PubMed:30404835). During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation (PubMed:30404835). Contributes to CROCC/rootletin filament formation (PubMed:30404835). {ECO:0000269|PubMed:30404835}.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding LRRC45 0.2
Publications: 1
+ down-regulates activity img/direct_inhibition.png phosphorylation CCDC102B 0.2
Publications: 1
+ up-regulates activity img/direct-activation.png relocalization CCDC102B 0.2
Publications: 1
+ up-regulates activity img/direct-activation.png binding CROCC 0.2
Publications: 1