Summary

Name BLOC1S3
Full Name Biogenesis of lysosome-related organelles complex 1 subunit 3
Synonyms BLOC-1 subunit 3 | BLOS3
Primary ID Q6QNY0
Links - -
Type protein
Relations 2
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding BLOC-1 0.705
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation BLOC1S3 0.2
Publications: 1