4.0
Summary
| Name |  CEP68View Modifications |
| Full Name | Centrosomal protein of 68 kDa |
| Synonyms | Cep68 | KIAA0582 |
| Primary ID | Q76N32 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Involved in maintenance of centrosome cohesion, probably as part of a linker structure which prevents centrosome splitting (PubMed:18042621). Required for localization of CDK5RAP2 to the centrosome during interphase (PubMed:24554434, PubMed:25503564). Contributes to CROCC/rootletin filament formation (PubMed:30404835). {ECO:0000269|PubMed:18042621, ECO:0000269|PubMed:24554434, ECO:0000269|PubMed:25503564, ECO:0000269|PubMed:30404835}. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PLK1 | down-regulates quantity by destabilization 
phosphorylation
|
CEP68 | 0.44 |
| Publications: | 1 | |||
| + | SCF-betaTRCP | down-regulates quantity by destabilization
ubiquitination
|
CEP68 | 0.337 |
| Publications: | 1 | |||
| + | CEP68 | up-regulates activity 
relocalization
|
CDK5RAP2 | 0.452 |
| Publications: | 1 | |||
| + | CEP68 | up-regulates activity
relocalization
|
PCNT | 0.34 |
| Publications: | 1 | |||
| + | NEK2 | down-regulates quantity by destabilization
phosphorylation
|
CEP68 | 0.252 |
| Publications: | 1 | Organism: | Homo Sapiens | |