3.0
Summary
| Name |  KDM3BView Modifications |
| Full Name | Lysine-specific demethylase 3B |
| Synonyms | JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, [histone H3]-dimethyl-L-lysine(9) demethylase 3B | C5orf7, JHDM2B, JMJD1B, KIAA1082 |
| Primary ID | Q7LBC6 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | KDM3B | down-regulates activity 
demethylation
|
H3-3A | 0.2 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | KDM3B | down-regulates activity
demethylation
|
H3C1 | 0.2 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | KDM3B | down-regulates activity
demethylation
|
H3-4 | 0.2 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | KDM3B | up-regulates quantity by expression 
transcriptional regulation
|
PPARA | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | KDM3B | up-regulates quantity by expression
transcriptional regulation
|
UCP1 | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | 2-oxoglutarate(2-) | up-regulates activity
chemical activation
|
KDM3B | 0.8 |
| Publications: | 1 | |||