Relation Results

Summary

Name KTN1
Full Name Kinectin
Synonyms CG-1 antigen, Kinesin receptor | CG1, KIAA0004
Primary ID Q86UP2
Links - -
Type protein
Relations 2
Function Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregatio ...
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Type: Score: Layout: SPV 
0.5930.2KTN1KIF5BEGFR

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Relations
Regulator
Mechanism
target
score ℹ
+ KTN1up-regulates img/direct-activation.png binding KIF5B 0.593
Identifier Residue Sequence Organism Cell Line
SIGNOR-128092 Homo sapiens
pmid sentence
This study demonstrated the effect of kinectin-kinesin interaction on lysosome dynamics and observed that the kinesin-binding domain of kinectin can significantly enhance the mt-stimulated atpase activity of kinesin.
Publications: 1 Organism: Homo Sapiens
+ KTN1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation EGFR 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259906 Homo sapiens
pmid sentence
Collectively, our findings revealed a novel mechanism wherein MALAT1 interacts with c-MYC to transactivate KTN1 for enhancing EGFR protein expression, which finally contributes to the development of cSCC.
Publications: 1 Organism: Homo Sapiens
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