| Name
|
 TP53INP2
|
| Full Name |
Tumor protein p53-inducible nuclear protein 2 |
| Synonyms |
Diabetes and obesity-regulated gene, p53-inducible protein U, PIG-U | C20orf110, DOR, PINH |
| Primary ID |
Q8IXH6 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
3 |
| Function |
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. |
3.0
binding
phosphorylation