3.0
Summary
| Name |  TP53INP2
|
| Full Name | Tumor protein p53-inducible nuclear protein 2 |
| Synonyms | Diabetes and obesity-regulated gene, p53-inducible protein U, PIG-U | C20orf110, DOR, PINH |
| Primary ID | Q8IXH6 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. |
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