Summary

Name BRK1
Full Name Protein BRICK1
Synonyms BRK1 | C3orf10
Primary ID Q8WUW1
Links - -
Type protein
Relations 5
Function Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ BRK1form complex img/form-complex.png binding WRC complex 0.859
Publications: 1 Organism: Homo Sapiens
+ BRK1up-regulates activity img/direct-activation.png binding NHS 0.2
Publications: 1 Organism: Homo Sapiens
+ NRF1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation BRK1 0.2
Publications: 1 Organism: Homo Sapiens
+ BRK1form complex img/form-complex.png binding WAVE complex 0.842
Publications: 1 Organism: Homo Sapiens
+ BRK1down-regulates img/indirect_inhibition.png Neurite_outgrowth 0.7
Publications: 1 Organism: Homo Sapiens