Name	TFAP2C
Full Name	Transcription factor AP-2 gamma
Synonyms	AP2-gamma, Activating enhancer-binding protein 2 gamma, Transcription factor ERF-1 \|
Primary ID	Q92754
Links	- -
Type	protein
Relations	5
Function	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.