| + |
TFAP2C | up-regulates 
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269262 |
|
|
|
|
| pmid |
sentence |
| 31583686 |
SOX17 regulates TFAP2C, PRDM1 and PRDM14, thereby maintaining latent pluripotency and suppressing somatic differentiation. |
|
| Publications: |
1 |
| + |
POU5F1 | up-regulates
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242070 |
|
|
Homo sapiens |
Embryonic Stem Cell |
| pmid |
sentence |
| 16153702 |
Our results suggest that OCT4, SOX2, and NANOG contribute to pluripotency and self-renewal by activating their own genes and genes encoding components of key signaling pathways and by repressing genes that are key to developmental processes. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242067 |
|
|
Homo sapiens |
Embryonic Stem Cell |
| pmid |
sentence |
| 25126380 |
Sex determining region Y-box 2 (Sox2), a member of the SoxB1 transcription factor family, is an important transcriptional regulator in pluripotent stem cells (PSCs). Together with octamer-binding transcription factor 4 and Nanog, they co-operatively control gene expression in PSCs and maintain their pluripotency. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
SOX2 | up-regulates
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242002 |
|
|
Homo sapiens |
Embryonic Stem Cell |
| pmid |
sentence |
| 25126380 |
Sex determining region Y-box 2 (Sox2), a member of the SoxB1 transcription factor family, is an important transcriptional regulator in pluripotent stem cells (PSCs). Together with octamer-binding transcription factor 4 and Nanog, they co-operatively control gene expression in PSCs and maintain their pluripotency. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242064 |
|
|
Homo sapiens |
Embryonic Stem Cell |
| pmid |
sentence |
| 16153702 |
Our results suggest that OCT4, SOX2, and NANOG contribute to pluripotency and self-renewal by activating their own genes and genes encoding components of key signaling pathways and by repressing genes that are key to developmental processes. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
PRDM1 | up-regulates
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269263 |
|
|
|
|
| pmid |
sentence |
| 31583686 |
SOX17 regulates TFAP2C, PRDM1 and PRDM14, thereby maintaining latent pluripotency and suppressing somatic differentiation. |
|
| Publications: |
1 |
| + |
NANOG | up-regulates
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242073 |
|
|
Homo sapiens |
Embryonic Stem Cell |
| pmid |
sentence |
| 25126380 |
Sex determining region Y-box 2 (Sox2), a member of the SoxB1 transcription factor family, is an important transcriptional regulator in pluripotent stem cells (PSCs). Together with octamer-binding transcription factor 4 and Nanog, they co-operatively control gene expression in PSCs and maintain their pluripotency. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-242076 |
|
|
Homo sapiens |
Embryonic Stem Cell |
| pmid |
sentence |
| 16153702 |
Our results suggest that OCT4, SOX2, and NANOG contribute to pluripotency and self-renewal by activating their own genes and genes encoding components of key signaling pathways and by repressing genes that are key to developmental processes. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
PRDM14 | up-regulates
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269261 |
|
|
|
|
| pmid |
sentence |
| 31583686 |
SOX17 regulates TFAP2C, PRDM1 and PRDM14, thereby maintaining latent pluripotency and suppressing somatic differentiation. |
|
| Publications: |
1 |
| + |
Embryonic stem cell-specific SWI/SNF | up-regulates
|
Pluripotency |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270728 |
|
|
Mus musculus |
Embryonic Stem Cell |
| pmid |
sentence |
| 19279220 |
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
4.0
Pluripotency