Relation Results

Summary

Name DDX17
Full Name Probable ATP-dependent RNA helicase DDX17
Synonyms DEAD box protein 17, DEAD box protein p72, RNA-dependent helicase p72
Primary ID Q92841
Links - -
Type protein
Relations 3
Pathways YAP/TAZ regulation
Function As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-m ...
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Type: Score: Layout: SPV 
0.5580.20.426DDX17Microprocessor complexYAP/TAZRNA helicases DDX5/DDX17

Relations

Regulator
Mechanism
target
score
+ up-regulates activity img/direct-activation.png binding Microprocessor complex 0.558
Identifier Residue Sequence Organism Cell Line
SIGNOR-277660 Homo sapiens
pmid sentence
In addition, nuclear YAP has also been found to regulate miRNA processing. Nuclear YAP/TAZ bind and sequester DEAD box helicase 17 (DDX17) (also known as p72) to repress its association with Microprocessor, a complex that regulates miRNA processing (Figure 3B).
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding DDX17 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-277659 Homo sapiens
pmid sentence
In addition, nuclear YAP has also been found to regulate miRNA processing. Nuclear YAP/TAZ bind and sequester DEAD box helicase 17 (DDX17) (also known as p72) to repress its association with Microprocessor, a complex that regulates miRNA processing (Figure 3B).
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding RNA helicases DDX5/DDX17 0.426
Identifier Residue Sequence Organism Cell Line
SIGNOR-149961 Homo sapiens
pmid sentence
We have found that the rna helicases p68/p72 are myod-associated proteins and that the noncoding rna sra also immunoprecipitates with myod. In vitro and in vivo experiments indicated that both p68/p72 and sra are coactivators of myod.
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
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