Summary

Name PERP
Full Name p53 apoptosis effector related to PMP-22
Synonyms Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW | KCP1, KRTCAP1, PIGPC1, THW
Primary ID Q96FX8
Links - -
Type protein
Relations 3
Function Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates quantity img/direct_inhibition.png ubiquitination NFKB1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PERP 0.609
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PERP 0.626
Publications: 1 Organism: Homo Sapiens