+ |
PERP | down-regulates quantity
ubiquitination
|
NFKB1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255843 |
|
|
Homo sapiens |
|
pmid |
sentence |
25860612 |
We identify KPC1 as the Ub ligase (E3) that binds to the ankyrin repeats domain of p105, ubiquitinates it, and mediates its processing both under basal conditions and following signaling |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TP63 | up-regulates quantity by expression
transcriptional regulation
|
PERP |
0.609 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255136 |
|
|
Homo sapiens |
|
pmid |
sentence |
21965674 |
SATB2 attenuates p63-mediated gene expression of perp (p53 apoptosis effector related to PMP-22), a critical downstream target gene during development, and specifically decreases p63 perp promoter binding. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TP53 | up-regulates quantity by expression
transcriptional regulation
|
PERP |
0.626 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-75877 |
|
|
Homo sapiens |
|
pmid |
sentence |
10733530 |
Perp induction is linked to p53-dependent apoptosis, including in response to e2f-1-driven hyperproliferation. Furthermore, analysis of the perp promoter suggests that perp is directly activated by p53. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |