4.0
Summary
| Name |  NSD1View Modifications |
| Full Name | Histone-lysine N-methyltransferase, H3 lysine-36 specific |
| Synonyms | Androgen receptor coactivator 267 kDa protein, Androgen receptor-associated protein of 267 kDa, H3-K36-HMTase, H4-K20-HMTase, Lysine N-methyltransferase 3B, Nuclear receptor-binding SET domain-containing protein 1, NR-binding SET domain-containing protein | ARA267, KMT3B |
| Primary ID | Q96L73 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Histone methyltransferase that dimethylates Lys-36 of histone H3 (H3K36me2). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | NSD1 | up-regulates 
methylation
|
RELA | 0.462 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | NSD1 | up-regulates
methylation
|
NfKb-p65/p50 | 0.462 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NSD1 | up-regulates quantity by expression
transcriptional regulation
|
PRB4 | 0.344 |
| Publications: | 1 | Organism: | Homo Sapiens | |