| + |
TCF12 | form complex 
binding
|
MYOD/HEB |
0.674 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-241119 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16847330 |
The MyoD family of basic helix-loop-helix transcription factors function as heterodimers with members of the E-protein family to induce myogenic gene activation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ID3 | down-regulates activity 
binding
|
TCF12 |
0.465 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-241152 |
|
|
Mus musculus |
C3H10T1/2 Cell |
| pmid |
sentence |
| 9242638 |
All three Ids bound with high affinity to E proteins .Each Id was able to disrupt the ability of E protein-MyoD complexes to transactivate from a muscle creatine kinase reporter construct in vivo. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
ID2 | down-regulates activity
binding
|
TCF12 |
0.55 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-241131 |
|
|
Mus musculus |
C3H10T1/2 Cell |
| pmid |
sentence |
| 9242638 |
All three Ids bound with high affinity to E proteins .Each Id was able to disrupt the ability of E protein-MyoD complexes to transactivate from a muscle creatine kinase reporter construct in vivo. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
TCF12 | up-regulates quantity by expression 
transcriptional regulation
|
NOTCH3 |
0.257 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-197517 |
|
|
Homo sapiens |
T-lymphocyte |
| pmid |
sentence |
| 22577461 |
Hebalt positively regulates t-cell genes, such as pt_ and notch3 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NOTCH1 | up-regulates quantity by expression
transcriptional regulation
|
TCF12 |
0.366 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-197514 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22577461 |
E2a positively regulates notch1 expression, which induces the expression of hebalt, bcl11b, and il7r. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TCF12 | up-regulates quantity by expression
transcriptional regulation
|
PTCRA |
0.326 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-197520 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22577461 |
Hebalt positively regulates t-cell genes, such as pt_ and notch3 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ID1 | down-regulates activity
binding
|
TCF12 |
0.582 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-241104 |
|
|
Mus musculus |
C3H10T1/2 Cell |
| pmid |
sentence |
| 9242638 |
All three Ids bound with high affinity to E proteins .Each Id was able to disrupt the ability of E protein-MyoD complexes to transactivate from a muscle creatine kinase reporter construct in vivo. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
4.0
TCF12
- 
- 