Summary

Name GPR87
Full Name G protein-coupled receptor 87
Synonyms G protein-coupled receptor 95 | GPR95
Primary ID Q9BY21
Links - -
Type protein
Relations 2
Function Receptor for lysophosphatidic acid (LPA) (PubMed:17905198). Necessary for p53/TP53-dependent survival in response to DNA damage (PubMed:19602589). Promotes the Hippo-YAP signaling pathway and thereby modulates glycolysis and oxidative stress production by the regulation of hexokinase-2/HK2 (PubMed:35843477). {ECO:0000269|PubMed:17905198, ECO:0000269|PubMed:19602589, ECO:0000269|PubMed:35843477}.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding GNAI1
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ
Publications: 1 Organism: Homo Sapiens