3.0
Summary
| Name |  NUF2
|
| Full Name | Kinetochore protein Nuf2 |
| Synonyms | hNuf2, hNuf2R, hsNuf2, Cell division cycle-associated protein 1 | CDCA1, NUF2R |
| Primary ID | Q9BZD4 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). |
binding
transcriptional regulation