| + |
PRKD1 | up-regulates activity 
phosphorylation
|
MFF |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275943 |
Ser155 |
GRLKRERsMSENAVR |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275942 |
Ser172 |
GQLVRNDsLWHRSDS |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275948 |
Ser275 |
DNVRYGIsNIDTTIE |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Publications: |
3 |
| + |
PRKD3 | up-regulates activity
phosphorylation
|
MFF |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275945 |
Ser155 |
GRLKRERsMSENAVR |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275940 |
Ser172 |
GQLVRNDsLWHRSDS |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275946 |
Ser275 |
DNVRYGIsNIDTTIE |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Publications: |
3 |
| + |
PRKAA1 | up-regulates activity
phosphorylation
|
MFF |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-245953 |
Ser155 |
GRLKRERsMSENAVR |
Homo sapiens |
|
| pmid |
sentence |
| 26816379 |
A screen for substrates of AMPK identified mitochondrial fission factor (MFF), a mitochondrial outer-membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fission. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-249656 |
Ser172 |
GQLVRNDsLWHRSDS |
Homo sapiens |
|
| pmid |
sentence |
| 26816379 |
A screen for substrates of AMPK identified mitochondrial fission factor (MFF), a mitochondrial outer-membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fission. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
PRKD2 | up-regulates activity
phosphorylation
|
MFF |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275947 |
Ser155 |
GRLKRERsMSENAVR |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275941 |
Ser172 |
GQLVRNDsLWHRSDS |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275949 |
Ser275 |
DNVRYGIsNIDTTIE |
|
|
| pmid |
sentence |
| 34010649 |
The mitochondrial fission factor (MFF), the main mitochondrial receptor for the Dynamin-related protein 1 (DRP1), is directly phosphorylated by Protein Kinase D (PKD) specifically during mitosis. PKD-dependent MFF phosphorylation is required and sufficient for mitochondrial fission in mitotic but not in interphasic cells.|PKD directly phosphorylates MFF on serines 155, 172, and 275 |
|
| Publications: |
3 |
| + |
AMPK | up-regulates activity
phosphorylation
|
MFF |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-245948 |
Ser155 |
GRLKRERsMSENAVR |
Homo sapiens |
U2-OS Cell |
| pmid |
sentence |
| 26816379 |
A screen for substrates of AMPK identified mitochondrial fission factor (MFF), a mitochondrial outer-membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fission. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-249655 |
Ser172 |
GQLVRNDsLWHRSDS |
Homo sapiens |
U2-OS Cell |
| pmid |
sentence |
| 26816379 |
A screen for substrates of AMPK identified mitochondrial fission factor (MFF), a mitochondrial outer-membrane receptor for DRP1, the cytoplasmic guanosine triphosphatase that catalyzes mitochondrial fission. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
MFF | up-regulates 
|
Mitochondrial_fission |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272983 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33610749 |
These proteins include the classical mitochondrial fusion (MFN1, MFN2, and OPA1) and fission proteins (DRP1, MFF, FIS1, etc.) as well as several other proteins that are directly or indirectly involved in these processes (e.g. YME1L, OMA1, INF2, GDAP1, MIC13, etc. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MFF | up-regulates activity
relocalization
|
DNM1L |
0.629 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-245957 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21149567 |
Mff functions as an essential factor in mitochondrial recruitment of Drp1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
MFF
- 
- 