4.0
Summary
| Name |  RBSNView Modifications |
| Full Name | Rabenosyn-5 |
| Synonyms | 110 kDa protein, FYVE finger-containing Rab5 effector protein rabenosyn-5, RAB effector RBSN, Zinc finger FYVE domain-containing protein 20 | ZFYVE20 |
| Primary ID | Q9H1K0 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388). |
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