3.0
Summary
| Name |  TAOK3View Modifications |
| Full Name | Serine/threonine-protein kinase TAO3 |
| Synonyms | Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, hKFC-A, Thousand and one amino acid protein 3 | DPK, JIK, KDS, MAP3K18 |
| Primary ID | Q9H2K8 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | TAOK3 | up-regulates activity 
phosphorylation
|
TAOK3 | 0.2 |
| Publications: | 2 | Organism: | Chlorocebus Aethiops | |
| + | TAOK3 | up-regulates
phosphorylation
|
STK3/4 | 0.295 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | TAOK3 | up-regulates
phosphorylation
|
STK3 | 0.295 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | TAOK3 | up-regulates
phosphorylation
|
STK4 | 0.287 |
| Publications: | 1 | Organism: | Homo Sapiens | |