Summary

Name CLK4
Full Name Dual specificity protein kinase CLK4
Synonyms CDC-like kinase 4
Primary ID Q9HAZ1
Links - -
Type protein
Relations 1
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation ABL1 0.08
Publications: 1 Organism: Homo Sapiens