| + |
FGF2 | up-regulates quantity by expression 
transcriptional regulation
|
ANKH |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252193 |
|
|
Homo sapiens |
MC3T3-E1(C4) Cell |
| pmid |
sentence |
| 19049325 |
FGF2 increases PC-1 and Ank expression while inhibiting Tnap expression in primary pre-osteoblast cells. Additionally, we show that the induction of PC-1 by FGF2 is cell type specific and mediated by the transcription factor, Runx2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TGFB1 | up-regulates quantity by expression
transcriptional regulation
|
ANKH |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252201 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20930330 |
TGF-β1 was shown to stimulate ANK and PC-1 expression in articular chondrocytes, and subsequent ePPi level, as well as to increase ePi uptake by inducing PiT-1 expression in a chondrogenic cell line. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
ANKH
- 
- 