Summary

Name PTPRH
Full Name Receptor-type tyrosine-protein phosphatase H
Synonyms R-PTP-H, Stomach cancer-associated protein tyrosine phosphatase 1, SAP-1, Transmembrane-type protein-tyrosine phosphatase type H | SAP1
Primary ID Q9HD43
Links - -
Type protein
Relations 6
Function Protein phosphatase that may contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion-associated substrates and thus negatively regulating integrin-promoted signaling processes. Induces apoptotic cell death by at least two distinct mechanisms

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png dephosphorylation INSR 0.273
Publications: 4 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation EGFR 0.292
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation GHR 0.298
Publications: 1 Organism: Cricetulus Griseus