+ |
PRKACA | up-regulates
phosphorylation
|
KCNK9 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-172466 |
Ser373 |
RLMKRRKsV |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
21357689 |
Patch clamp analysis, flow cytometry, and immunocytochemistry studies of hek293 transfected with wt hk2p3.1 and cultured in the presence of pka activators or inhibitors all confirm that activation of pka resulted in an increase in hk2p3.1 current expression (figs. 4_4?6) and demonstrate the dynamic regulatory effect of pka activity on k2p3.1 channel expression. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
PKC | down-regulates activity
phosphorylation
|
KCNK9 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-276059 |
Thr341 |
IEEISPStLKNSLFP |
Homo sapiens |
TsA-201 Cell |
pmid |
sentence |
17374744 |
PKC acts directly on hTASK3 channels to phosphorylate an identified amino acid in the C terminus region (Thr341), thereby reducing channel current. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |