Summary

Name HEYL
Full Name Hairy/enhancer-of-split related with YRPW motif-like protein
Synonyms hHeyL, Class B basic helix-loop-helix protein 33, bHLHb33, Hairy-related transcription factor 3, HRT-3, hHRT3 | BHLHB33, HRT3
Primary ID Q9NQ87
Links - -
Type protein
Relations 3
Function Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HEYL 0.2
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Smooth Muscle
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HEYL 0.593
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Smooth Muscle
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HEYL 0.594
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Smooth Muscle