| + |
CDC7 |
phosphorylation
|
RAD18 |
0.502 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-170049 |
Ser434 |
IQEVLSSsESDSCNS |
Homo sapiens |
|
| pmid |
sentence |
| 21098111 |
Although the cdc7/rad18 interaction and phosphorylation at s434 are induced by dna damage, s434 was also observed to be phosphorylated basally |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Ub:E2 | up-regulates activity 
ubiquitination
|
RAD18 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271095 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 34199813 |
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAD18 | up-regulates
ubiquitination
|
PCNA |
0.841 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-187705 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19706603 |
Rad5 interacts with the e3 ligase rad18, which is initially required to monoubiquitinate pcna |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNF8 | up-regulates
binding
|
RAD18 |
0.424 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-185593 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19396164 |
Rnf8 depletion also significantly reduced the accumulation of rad18 to chromatin fraction after ir |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
RAD18
- 
- 