Relation Results

Summary

Name ATG3
Full Name Ubiquitin-like-conjugating enzyme ATG3
Synonyms Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96 | APG3, APG3L
Primary ID Q9NT62
Links - -
Type protein
Relations 5
Pathways Autophagy
Function E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like cov ...
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Type: Score: Layout: SPV 
0.8730.7810.8470.8340.855ATG3GABARAPL2MAP1LC3CGABARAPMAP1LC3BMAP1LC3A

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Relations
Regulator
Mechanism
target
score ℹ
+ ATG3up-regulates activity img/direct-activation.png binding GABARAPL2 0.873
Identifier Residue Sequence Organism Cell Line
SIGNOR-141926 in vitro
pmid sentence
Three human atg8 (hatg8) homologs, lc3, gabarap, and gate-16, have been characterized as modifiers in reactions mediated by hatg7 (an e1-like enzyme) and hatg3 (an e2-like enzyme)
Publications: 1 Organism: In Vitro
Pathways:Autophagy
+ MAP1LC3Cup-regulates activity img/direct-activation.png binding ATG3 0.781
Identifier Residue Sequence Organism Cell Line
SIGNOR-191552 Mus musculus MEF Cell
pmid sentence
Lc3-i is activated by the same atg7 involved in atg12 conjugation, transferred to atg3, a second e2-like enzyme, and finally conjugated to pe
Publications: 1 Organism: Mus Musculus
Pathways:Autophagy
+ ATG3up-regulates activity img/direct-activation.png binding GABARAP 0.847
Identifier Residue Sequence Organism Cell Line
SIGNOR-141868 in vitro
pmid sentence
Three human atg8 (hatg8) homologs, lc3, gabarap, and gate-16, have been characterized as modifiers in reactions mediated by hatg7 (an e1-like enzyme) and hatg3 (an e2-like enzyme)
Publications: 1 Organism: In Vitro
Pathways:Autophagy
+ MAP1LC3Bup-regulates img/direct-activation.png binding ATG3 0.834
Identifier Residue Sequence Organism Cell Line
SIGNOR-191549 Homo sapiens
pmid sentence
Lc3-i is activated by the same atg7 involved in atg12 conjugation, transferred to atg3, a second e2-like enzyme, and finally conjugated to pe.
Publications: 1 Organism: Homo Sapiens
+ MAP1LC3Aup-regulates img/direct-activation.png binding ATG3 0.855
Identifier Residue Sequence Organism Cell Line
SIGNOR-191543 Homo sapiens
pmid sentence
Lc3-i is activated by the same atg7 involved in atg12 conjugation, transferred to atg3, a second e2-like enzyme, and finally conjugated to pe.
Publications: 1 Organism: Homo Sapiens
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