3.0
Summary
| Name |  WWOXView Modifications |
| Full Name | WW domain-containing oxidoreductase |
| Synonyms | Fragile site FRA16D oxidoreductase, Short chain dehydrogenase/reductase family 41C member 1 | FOR, SDR41C1, WOX1 |
| Primary ID | Q9NZC7 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm. |
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phosphorylation
transcriptional regulation