Relation Results

Summary

Name MYOF
Full Name Myoferlin
Synonyms Fer-1-like protein 3 | FER1L3, KIAA1207
Primary ID Q9NZM1
Links - -
Type protein
Relations 4
Pathways Myofiber: Calcium-mediated fusion, Myoblast: Calcium-mediated fusion, Myoblast: GH-mediated fusion
Function Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membra ...
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Type: Score: Layout: SPV 
0.70.2MYOFMyoblast_fusionNFATC2

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Relations
Regulator
Mechanism
target
score ℹ
+ MYOFup-regulates img/indirect-activation.png Myoblast_fusion 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-255466 Homo sapiens
pmid sentence
Activated NFATc2 stimulates myoblast fusion through the increased production of IL-4 and myoferlin
Identifier Residue Sequence Organism Cell Line
SIGNOR-255973 Mus musculus
pmid sentence
These data support a role for myoferlin in the maturation of myotubes and the formation of large myotubes that arise from the fusion of myoblasts to multinucleate myotubes
Publications: 2 Organism: Homo Sapiens, Mus Musculus
+ NFATC2up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MYOF 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-255465 Homo sapiens
pmid sentence
Activated NFATc2 stimulates myoblast fusion through the increased production of IL-4 and myoferlin
Publications: 1 Organism: Homo Sapiens
Tissue: Skeletal Muscle
+ NFATC2up-regulates img/indirect-activation.png transcriptional regulation MYOF 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-255461 Homo sapiens
pmid sentence
Activated NFATc2 stimulates myoblast fusion through the increased production of IL-4 and myoferlin
Publications: 1 Organism: Homo Sapiens
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