Relation Results

Summary

Name CNTNAP2
Full Name Contactin-associated protein-like 2
Synonyms Cell recognition molecule Caspr2 | CASPR2, KIAA0868
Primary ID Q9UHC6
Links - -
Type protein
Relations 3
Function Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in ...
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Type: Score: Layout: SPV 
0.20.3310.481STOX1CNTNAP2TCF4CNTN1

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Relations
Regulator
Mechanism
target
score ℹ
+ STOX1down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation CNTNAP2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269065 Homo sapiens Hippocampus
pmid sentence
In this study we performed chromatin immunoprecipitation coupled to shotgun cloning to discover novel STOX1A target genes. Our results show that CNTNAP2, a member of the neurexin family, is directly downregulated by STOX1A.
Publications: 1 Organism: Homo Sapiens
+ TCF4up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CNTNAP2 0.331
Identifier Residue Sequence Organism Cell Line
SIGNOR-255390 Homo sapiens
pmid sentence
we show that TCF4 can transactivate the NRXN1β and CNTNAP2 promoters in luciferase assays.
Publications: 1 Organism: Homo Sapiens
+ CNTNAP2up-regulates activity img/direct-activation.png relocalization CNTN1 0.481
Identifier Residue Sequence Organism Cell Line
SIGNOR-269074 Mus musculus Sciatic Nerve
pmid sentence
These results suggest that the targeting of contactin to different axonal domains may be determined, in part, via its association with Caspr.
Publications: 1 Organism: Mus Musculus
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