| + |
RIMBP3 | down-regulates activity 
binding
|
RIMS3 |
0.289 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264370 |
|
|
Rattus norvegicus |
PC-12 Cell |
| pmid |
sentence |
| 11988172 |
SH3 domains of RBPs interact with RIMs. The enhancement of depolarization-induced secretion in PC12 cells by fusion proteins that suppress the associations of RBPs with RIMs and α1 suggests that RBPs may repress RIMs, either directly or through associated proteins. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RIMS3 | up-regulates activity 
binding
|
CACNA1D |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264357 |
|
|
Homo sapiens |
Cochlear Hair Cell |
| pmid |
sentence |
| 28642685 |
Here, we report an interaction of the C2B domain of RIM2α and RIM3γ with the C-terminus of the pore-forming α-subunit of CaV1.3 channels (CaV1.3α1), which mediate stimulus-secretion coupling at the ribbon synapses of cochlear inner hair cells (IHCs). In conclusion, we propose that RIM2α and RIM3γ directly interact with the C-terminus of the pore-forming subunit of CaV1.3 Ca2+ channels and positively regulate their plasma membrane expression in HEK293 cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RIMBP3B | down-regulates activity
binding
|
RIMS3 |
0.267 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264374 |
|
|
Rattus norvegicus |
PC-12 Cell |
| pmid |
sentence |
| 11988172 |
SH3 domains of RBPs interact with RIMs. The enhancement of depolarization-induced secretion in PC12 cells by fusion proteins that suppress the associations of RBPs with RIMs and α1 suggests that RBPs may repress RIMs, either directly or through associated proteins. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RIMS3 | up-regulates activity
relocalization
|
RAB3C |
0.262 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264380 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31679900 |
N-terminal interactions of RIMs with RAB3 and MUNC13 regulate DCV fusion. Through N-terminal interactions, RIMs position MUNC13 and recruit DCVs via RAB3, which is located on the vesicle |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RIMS3 | up-regulates activity
relocalization
|
RAB3A |
0.286 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264379 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31679900 |
N-terminal interactions of RIMs with RAB3 and MUNC13 regulate DCV fusion. Through N-terminal interactions, RIMs position MUNC13 and recruit DCVs via RAB3, which is located on the vesicle |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TSPOAP1 | down-regulates activity
binding
|
RIMS3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264373 |
|
|
Rattus norvegicus |
PC-12 Cell |
| pmid |
sentence |
| 11988172 |
SH3 domains of RBPs interact with RIMs. The enhancement of depolarization-induced secretion in PC12 cells by fusion proteins that suppress the associations of RBPs with RIMs and α1 suggests that RBPs may repress RIMs, either directly or through associated proteins. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RIMBP3C | down-regulates activity
binding
|
RIMS3 |
0.267 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264372 |
|
|
Rattus norvegicus |
PC-12 Cell |
| pmid |
sentence |
| 11988172 |
SH3 domains of RBPs interact with RIMs. The enhancement of depolarization-induced secretion in PC12 cells by fusion proteins that suppress the associations of RBPs with RIMs and α1 suggests that RBPs may repress RIMs, either directly or through associated proteins. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RIMBP2 | down-regulates activity
binding
|
RIMS3 |
0.285 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264371 |
|
|
Rattus norvegicus |
PC-12 Cell |
| pmid |
sentence |
| 11988172 |
SH3 domains of RBPs interact with RIMs. The enhancement of depolarization-induced secretion in PC12 cells by fusion proteins that suppress the associations of RBPs with RIMs and α1 suggests that RBPs may repress RIMs, either directly or through associated proteins. |
|
| Publications: |
1 |
Organism: |
Rattus Norvegicus |
| + |
RIMS3 | up-regulates activity
relocalization
|
UNC13B |
0.269 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264384 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31679900 |
N-terminal interactions of RIMs with RAB3 and MUNC13 regulate DCV fusion. Through N-terminal interactions, RIMs position MUNC13 and recruit DCVs via RAB3, which is located on the vesicle |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
RIMS3
- 
- 