| + |
RAB3C | up-regulates 
|
Dense-core_vesicle_exocytosis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264376 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31679900 |
Here, we identify the SEC4 ortholog RAB3 and its neuronal effector, RIM1, as essential molecules for neuropeptide and neurotrophin release from dense-core vesicles (DCVs) in mammalian neurons. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RIMS3 | up-regulates activity 
relocalization
|
RAB3C |
0.263 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264380 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31679900 |
N-terminal interactions of RIMs with RAB3 and MUNC13 regulate DCV fusion. Through N-terminal interactions, RIMs position MUNC13 and recruit DCVs via RAB3, which is located on the vesicle |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RIMS1 | up-regulates activity
relocalization
|
RAB3C |
0.431 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264382 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31679900 |
N-terminal interactions of RIMs with RAB3 and MUNC13 regulate DCV fusion. Through N-terminal interactions, RIMs position MUNC13 and recruit DCVs via RAB3, which is located on the vesicle |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RIMS2 | up-regulates activity
relocalization
|
RAB3C |
0.582 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264378 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31679900 |
N-terminal interactions of RIMs with RAB3 and MUNC13 regulate DCV fusion. Through N-terminal interactions, RIMs position MUNC13 and recruit DCVs via RAB3, which is located on the vesicle |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
RAB3C
- 
- 