| + |
CHKA | down-regulates activity
phosphorylation
|
VANGL2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278925 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31090542 |
CKI\u03b5-dependent phosphorylation increases Stbm turnover at junctions, and thus promotes complex sorting, while phosphorylation of Dsh decreases its turnover.|Interestingly, CKI\u03b5 has been implicated in phosphorylation of both Stbm and Dsh. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ROR2 | down-regulates activity
phosphorylation
|
VANGL2 |
0.593 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280111 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23140626 |
In support of this, ror2 mutants abolish Vangl2 activity gradient and localization, and ror2; vangl2 double mutants phenocopy the wnt5a limb phenotype (Gao et al., 2011).4.6.|This process is mediated by its receptor Ror2, which in turn phosphorylates Vangl2 and induces asymmetric localization of Vangl2, propagating an activity gradient of Vangl2 in the proximal direction (Gao et al., 2011). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |