Summary

Name VANGL2
Full Name Vang-like protein 2
Synonyms Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2 | KIAA1215, STB1
Primary ID Q9ULK5
Links - -
Type protein
Relations 1
Function Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation VANGL2 0.2
Publications: 1 Organism: Homo Sapiens