+ |
MAPK1 |
phosphorylation
|
ARHGAP26 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262944 |
Ser685 |
PMFSAPSsPMPTSST |
in vitro |
|
pmid |
sentence |
9525907 |
In vitro, purified mitogen-activated protein (MAP) kinase catalyzed the phosphorylation of Graf on serine 510, suggesting that Graf phosphorylation may be mediated through MAP kinase signaling. |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
MAPK3 |
phosphorylation
|
ARHGAP26 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262945 |
Ser685 |
PMFSAPSsPMPTSST |
in vitro |
|
pmid |
sentence |
9525907 |
In vitro, purified mitogen-activated protein (MAP) kinase catalyzed the phosphorylation of Graf on serine 510, suggesting that Graf phosphorylation may be mediated through MAP kinase signaling. |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
ARHGAP26 | down-regulates activity
gtpase-activating protein
|
RHOA |
0.613 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260481 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
32203420 |
We therefore developed a screening-compatible live-cell imaging assay, using FRET-based biosensors for the prototype GTPases RHOA, RAC1 and CDC4215,19,20 (Extended Data Fig. 2 and Supplementary Note 1)|We found catalytic activities for 45/75 RhoGEFs and 48/63 RhoGAPs| Our data thus not only reveal extensive promiscuity among regulators, but also that the inactivating RhoGAPs are less selective than the activating RhoGEFs (p-value=0.02)(Supplementary Table 2). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
Gbeta |
phosphorylation
|
ARHGAP26 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-270058 |
|
|
in vitro |
|
pmid |
sentence |
9525907 |
In vitro, purified mitogen-activated protein (MAP) kinase catalyzed the phosphorylation of Graf on serine 510, suggesting that Graf phosphorylation may be mediated through MAP kinase signaling. |
|
Publications: |
1 |
Organism: |
In Vitro |
+ |
ERK1/2 |
phosphorylation
|
ARHGAP26 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-270170 |
|
|
in vitro |
|
pmid |
sentence |
9525907 |
In vitro, purified mitogen-activated protein (MAP) kinase catalyzed the phosphorylation of Graf on serine 510, suggesting that Graf phosphorylation may be mediated through MAP kinase signaling. |
|
Publications: |
1 |
Organism: |
In Vitro |