+ |
ABL1 | up-regulates activity
phosphorylation
|
WASF3 |
0.565 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262299 |
Tyr151 |
KKDGLKFyTDPSYFF |
Homo sapiens |
MDA-MB-231 Cell |
pmid |
sentence |
17623672 |
WAVE3-Abl interaction promotes the tyrosine phosphorylation of WAVE3 by Abl, and STI-571, a specific inhibitor of Abl kinase activity, abrogates the Abl-mediated phosphorylation of WAVE3. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262300 |
Tyr248 |
HASDVTDySYPATPN |
Homo sapiens |
MDA-MB-231 Cell |
pmid |
sentence |
17623672 |
WAVE3-Abl interaction promotes the tyrosine phosphorylation of WAVE3 by Abl, and STI-571, a specific inhibitor of Abl kinase activity, abrogates the Abl-mediated phosphorylation of WAVE3. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262301 |
Tyr337 |
LPAQIIEyYNPSGPP |
Homo sapiens |
MDA-MB-231 Cell |
pmid |
sentence |
17623672 |
WAVE3-Abl interaction promotes the tyrosine phosphorylation of WAVE3 by Abl, and STI-571, a specific inhibitor of Abl kinase activity, abrogates the Abl-mediated phosphorylation of WAVE3. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-259077 |
Tyr486 |
SRRIAVEySDSDDDS |
Homo sapiens |
|
pmid |
sentence |
17623672 |
WAVE3-Abl interaction promotes the tyrosine phosphorylation of WAVE3 by Abl, and STI-571, a specific inhibitor of Abl kinase activity, abrogates the Abl-mediated phosphorylation of WAVE3. |
|
Publications: |
4 |
Organism: |
Homo Sapiens |
+ |
WASF3 | up-regulates activity
|
Metastasis |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-259078 |
|
|
Chlorocebus aethiops |
|
pmid |
sentence |
17623672 |
We have also shown that Abl targets and phosphorylates four tyrosine residues in WAVE3 and that the Abl-dependent phosphorylation of WAVE3 is critical for the stimulation of lamellipodia formation and cell migration. |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |