3.0
Summary
| Name |  MAP4K5View Modifications |
| Full Name | Mitogen-activated protein kinase kinase kinase kinase 5 |
| Synonyms | Kinase homologous to SPS1/STE20, KHS, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, MEKKK 5 |
| Primary ID | Q9Y4K4 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MAP4K5 | down-regulates 
phosphorylation
|
GSK3B | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CRK | up-regulates activity 
binding
|
MAP4K5 | 0.371 |
| Publications: | 1 | Organism: | In Vitro | |
| + | MAP4K5 | down-regulates activity
phosphorylation
|
GSK3B/Axin/APC | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KRAS | up-regulates 
|
MAP4K5 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MAP4K5 | up-regulates
|
MAP3K1 | 0.432 |
| Publications: | 1 | Organism: | Homo Sapiens | |