3.0
Summary
| Name |  NOX1View Modifications |
| Full Name | NADPH oxidase 1 |
| Synonyms | NOX-1, Mitogenic oxidase 1, MOX-1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1 | MOX1, NOH1 |
| Primary ID | Q9Y5S8 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCB | up-regulates activity 
phosphorylation
|
NOX1 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | NOXA1 | up-regulates activity
binding
|
NOX1 | 0.743 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NOX1 | up-regulates quantity
chemical modification
|
superoxide | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NOX1 | up-regulates
|
ROS | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |